Autoimmunity and Human Health

Dr. Lyons-Weiler's lecture on the ease with which autoimmune conditions can be caused in animals to allow pharmaceutical companies to test drugs on the treatment of autoimmune conditions. This is one of many lectures in the course on Autoimmunity and Human Health. That course, and many other stellar rotating courses, may be found at IPAK-EDU: http://ipak-edu.org/registration

This is the introductory course over lecture for the course, "Autoimmunity and Human Health" offered at IPAK-EDU. Register for this course and other amazing courses at http://ipak-edu.org/registration SYLLABUS (subject to change) Instructor: James Lyons-Weiler, PhD In this class, students will learn the fundamentals of autoimmunity and acquire a working knowledge of the systems biology, cellular and molecular biology and of disease pathophysiologies involved in autoimmunity. This is equivalent to a 300-400 level college course. We'll have live Zoom class meetings w/Q&A and students can access the video lectures if they miss a class. Prerequisites:: IPAK-EDU Biology of Immunology COURSE/TOPIC OUTLINE A. Immune System Overview Week 1: Overview Lecture: Autoimmunity & The Human Immune System Overview Week 2: IgE, Mast Cells, and Eosinophils – what are they and how do they work? What happens when they go wrong? B. Allergy vs Autoimmunity Week 3: Allergy vs Autoimmunity - What’s the Difference? Week 4: Hypersensitivity – how allergies can trigger autoimmunity Week 5: Immune Tolerance and Autoimmune Regulation – how our bodies prevent autoimmunity Week 6: Genetics & Environment in Autoimmunity – What role do genetics play in autoimmune disease? How does our environment affect us? How do G&E interact? Week 7: Mold & Pathogens- How can mold & pathogens affect autoimmune diseases? Week 8: Parasites and Autoimmunity C. Our Microbiome & Autoimmunity Week 9: The Microbiome & Autoimmunity - Exploring the relationship between the microbiome and autoimmune diseases D. Diet, Food, & Autoimmunity Week 10: Diet & Food - How do diet and food play a role in autoimmune disease? E. Chronic Fatigue Syndrome (CFS) & Macrophagic Myofasciitis (MMF) Week 11: Chronic Fatigue Syndrome (CFS) Week 12: Macrophagic Myofasciitis (MMF) F. Autoimmune Diseases of the Brain and CNS Week 13: Autoimmunogical basis of neurodegenerative diseases Week 14: Bipolar Disorder – immunological factors, causes, diagnosis Week 15: Cancer - Role of autoimmunity in cancer development; treatment options for cancer patients with autoimmune disorders Week 16: Celiac Disease and Gluten Intolerances – Diagnosis; long-term effects Week 17: Chronic Pain - Role of autoimmunity in chronic pain development Week 18. Dementia – Role of autoimmune diseases in dementia development Week 19: Depression - Role of autoimmune diseases in depression development Week 20: Endocrine Disorders– Role of autoimmune diseases in endocrine development Week 21: Obsessive Compulsive Disorder(OCD)– Role of autoimmune diseases in OCD development; treatment options for OCD patients with autoimmune disorders Week 22: Peripheral Neuropathy– Causes/Risk factors/Treatment overview as it relates to those suffering from an array of conditions including postural orthostatic tachycardia syndrome(POTS). Week 23: Autoimmune Diseases of the Autonomic Nervous System 1. Postural Orthostatic Tachycardia Syndrome (POTS) 2. Neuromyotonia (Isaacs Syndrome) 3. Small Fiber Neuropathy 4. Autoimmune Autonomic Ganglionopathy (AAG) 5. Autoimmune Gastropathy 6. Multiple System Atrophy (MSA) 7. Autoimmune Cholangiopathy Week 24 PANDAS and PANS