Omicron, the vaccine we failed to make
Omicron now and risky London research
https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---30-march-2023
Covid, 3.6 million new cases (down 27% on the month)
25 000 deaths (down 39% on the month)
Hospital admissions, down 9%
ICU admissions down 5%
As of 26 March 2023
761 million confirmed cases
6.8 million deaths
Current trends in reported COVID-19 cases are underestimates of the true number of global infections and reinfections.
Variants, geographic spread and prevalence
27 February to 26 March 2023 (28 days),
54, 922 SARS-CoV-2 sequences
WHO closely tracking variant of interest, XBB.1.5
Six variants under monitoring (VUMs).
BQ.1, BA.2.75, CH.1.1, XBB, XBF and XBB.1.16
XBB.1.16 is a recombinant of BA.2.10.1 and BA.2.75
(three additional mutations in the SARS-CoV-2 spike protein)
Reports do not indicate a rise in hospitalizations, ICU admissions, or deaths due to XBB.1.16.
Globally
XBB.1.5 accounts for 45.1% of cases
BQ.1, BA.2.75 declined
CH.1.1 and XBF remained stable
Civil Service, long covid, September and October 2022
https://www.telegraph.co.uk/politics/2023/03/31/twice-as-many-civil-servants-long-covid-national-average/
10 – 10.8 %, declared the condition in autumn 2022
7.4 % affecting their day-to-day life
(3.3 % of the general public)
Year to March 2022
Poor mental health
Musculoskeletal problems
Others
Long covid
Periods off sick, less than 20 working days
32.4 % of all absences
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WHO, April fools?
WHO’s Strategic Advisory Group of Experts
https://www.who.int/news/item/28-03-2023-sage-updates-covid-19-vaccination-guidance
revised the roadmap for prioritizing the use of COVID-19 vaccines,
to reflect the impact of Omicron and high population-level immunity due to infection and vaccination.
The roadmap newly considers the cost-effectiveness of COVID-19 vaccination for those at lower risk
– namely healthy children and adolescents –
Revised roadmap reemphasizes the importance of vaccinating those still at-risk of severe disease,
mostly older adults and those with underlying conditions,
Chair Dr Hanna Nohynek.
“Countries should consider their specific context in deciding whether to continue vaccinating low risk groups,
like healthy children and adolescents,
while not compromising the routine vaccines that are so crucial for the health and well-being of this age group.”
The high priority group
and frontline health workers.
SAGE recommends an additional booster of either 6 or 12 months after the last dose,
Medium priority group
healthy adults – usually under the age of 50-60 – without comorbidities
Although additional boosters are safe for this group, SAGE does not routinely recommend them,
The low priority group
healthy children and adolescents aged 6 months to 17 years.
Primary and booster doses are safe and effective in children and adolescents.
The public health impact of vaccinating healthy children and adolescents is comparatively much lower than the established benefits of traditional essential vaccines for children
Vaccinating pregnant persons – including with an additional dose if more than 6 months have passed since the last dose – protects both them and the fetus
Other meeting highlights include:
Polio, OPV
Regional reports on measles
With measles cases increasing in all WHO regions in 2022
In 2021, with 25 million children missing out.
Status of new tuberculosis vaccines
Tuberculosis (TB) is a leading cause of death and a vaccine that prevents disease in adolescents and adults is urgently needed.
A substantial effort for vaccine development is underway, with several candidates in late-stage clinical trials
Malaria
Introducing the RTS,S malaria vaccine has resulted in a substantial reduction in severe malaria and all-cause mortality among age eligible children.
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Mild symptoms, high excess deaths
Covid symptom data mild, excess deaths high
https://health-study.joinzoe.com
Sore throat 59%
Runny nose 54%
Blocked nose 52%
Headache 51%
Sneezing 50%
Cough, no phlegm 49%
Cough with Phlegm 41%
Hoarse voice 36%
Muscle aches pains 27%
Fatigue 20%
Altered smell 20%
Dizzy light headed 19%
Swollen neck glands 17%
Sore eyes 16%
Loss of smell 16%
Chest pain tightness 14%
Short of breaths 13%
Earache 13%
Shivers or chills 13%
Fever 11%
https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregisteredweeklyinenglandandwalesprovisional/weekending17march2023
https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/coronaviruscovid19infectionsurveypilot/latest
England
Estimated number of people testing positive for COVID-19
1,493,200
Equating to 2.66% of the population,
or around 1 in 40 people.
Week ending 17 March 2023 (Week 11)
12,133 deaths registered in England and Wales
559 deaths mentioned novel coronavirus (COVID-19),
accounting for 4.6% of all deaths.
Of the 559 deaths involving COVID-19
67.3% (376 deaths) had this recorded as the underlying cause of death
The number of deaths was above the five-year average
In private homes 23.2% above, (674 excess deaths)
In hospitals 4.6% above,
(232 excess deaths)
In care homes 4.7% above,
(112 excess deaths)
In other settings 6.9% above, (55 excess deaths)
Number of deaths registered in the UK in the week ending 17 March 2023
13,683, (9.3% above the five-year average)
Thats 1,169 more deaths than the five-year average
Excess deaths
https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/monthlymortalityanalysisenglandandwales/december2022#excess-mortality-in-england-and-wales
The difference between the observed deaths within a period compared with the five-year average (2016 to 2019, and 2021)
Probably multifactorial
Excess deaths have occurred around the world
Let’s look for a common (or group of) underlying cause that would explain the tragedy.
It may transpire there is a common factor (s)
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London, risky covid research
Good point, we have seen the tragedy of this many times of course, one person, armed and with a grudge
British experiments
https://www.telegraph.co.uk/news/2023/03/18/how-british-experiments-risked-making-covid-pandemic-lethal/
Risked making the Covid pandemic ‘more lethal’
In testing, Imperial College London
Experiments took place in London
Supported by the UK Health Security Agency (UKHSA)
Cells were infected with delta and omicron,
at the same time,
to see which had a competitive advantage.
Professor Anton van der Merwe, molecular immunology, University of Oxford
Risked combining the two variants,
to produce something “more lethal”
Infected scientists, could walk out of the lab.
“Coronaviruses like Sars-CoV-2 are well known to ‘evolve’ by exchanging genetic material,
when two distinct viruses infect the same cell,”
This makes it much more likely that these two strains will recombine,
and create a more dangerous variant,
which could infect those doing the experiments,
who could then spread it into the community.”
Using delta and omicron, particularly risky,
from different lineages, with significant differences
Professor Anton van der Merwe,
There is more opportunity for recombination in animal experiments and selection for more dangerous variants because they involve more cells infected for longer periods,
Handling animals is also riskier in terms of transmission to the experimenter than handling cells.
Neither of these experiments are of any help in protecting us from Sars-CoV-2.
Dr Filippa Lentzos, Centre for Science and Security Studies King’s College London
“There has been a global boom in construction of labs handling dangerous pathogens, but this has not been accompanied by sufficient biosafety and biosecurity oversight.”
Imperial College London
“This government-backed research used viruses no more pathogenic than those already circulating within the population and will provide crucial insights that support government decision-making on how to manage the pandemic.
“It was conducted in a biosafety level three laboratory in line with strict government regulations, and received ongoing approval from the Health and Safety Executive.”
https://consteril.com/biosafety-levels-difference/
Wuhan IV, biosafety level 4 (BSL4)
One of 59 around the world
Three quarters in urban settings (like London)
Past lab leaks
Smallpox, swine flu, SARS, anthrax, foot and mouth disease
Report by King’s College London
https://www.kcl.ac.uk/fifty-nine-labs-around-world-handle-the-deadliest-pathogens-only-a-quarter-score-high-on-safety
Did the coronavirus SARS-CoV-2 result from high-risk research gone wrong?
The risk of future pandemics originating from research with dangerous pathogens is real.
BSL4 labs
Europe, 25 labs
North America, 14 and
Asia, 13
Australia, 4
Africa,3
With 3,000m² of lab space, the Wuhan Institute of Virology is the largest BSL4 lab in the world
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Vaccine injury staff increased from 4 to 80
UK, Vaccine injuries
https://www.telegraph.co.uk/news/2023/03/24/vaccine-damage-payment-scheme-boosts-staff-numbers-four-80-covid/
https://www.telegraph.co.uk/news/2023/03/27/young-women-had-35-times-higher-risk-death-heart-issues-astrazeneca/
The Vaccine Damage Payment Scheme (VDPS)
https://www.gov.uk/vaccine-damage-payment
Admin workers, 4 up to 80
20 fold increase
Increasing demand for Covid vaccine injury payments
A project, to digitalise application process
If you’re severely disabled as a result of a vaccination against certain diseases,
you could get a one-off tax-free payment of £120,000.
This is called a Vaccine Damage Payment.
You can also apply for this payment on behalf of someone who has died after becoming severely disabled because of certain vaccinations.
You could get a payment if you’re severely disabled and your disability was caused by vaccination against any of the following diseases:
• coronavirus (COVID-19)
• diphtheria
• haemophilus influenzae type b (Hib)
• human papillomavirus
• influenza, except for influenza caused by a pandemic influenza virus
• measles
• meningococcal group B (meningitis B)
• meningococcal group C (meningitis C)
• meningococcal group W (meningitis W)
• mumps
• pandemic influenza A (H1N1) 2009 (swine flu) - up to 31 August 2010
• pertussis (whooping cough)
• pneumococcal infection
• poliomyelitis
• rotavirus
• rubella (German measles)
• smallpox - up to 1 August 1971
• tetanus
• tuberculosis (TB)
You may also be able to get a payment if you’re severely disabled because,
your mother was vaccinated against one of the diseases in the list while she was pregnant
What counts as ‘severely disabled’?
Disablement is worked out as a percentage, and ‘severe disablement’ means at least 60% disabled.
This could be a mental or physical disablement,
and will be based on medical evidence from the doctors or hospitals involved in your treatment.
The Hausfeld Claimant group
A group of patients and families are now taking legal action against AstraZeneca,
after they suffered injury or bereavement as a result of complications from the Covid vaccine.
https://www.hausfeld.com/en-gb/news/claimant-group-brings-legal-claim-against-astrazeneca-under-consumer-protection-act-1987/
13 bereaved families, and 28 survivors,
“Vaccine Induced Thrombocytic Thrombocytopenia”
Consumer Protection Act 1987,
argues that the AstraZeneca vaccine was “defective”,
in that it was not as safe as individuals were entitled to expect.
VITT is now established as causatively linked with the AstraZeneca vaccine. (Hausfeld)
(18% case fatality rate)
Freedom of Information (FOI) March 2023
4,017 claims, submitted since Nov 1 2021.
Payment scheme taken over by NHS Business Services Authority in November 2021
https://www.nhsbsa.nhs.uk
Of the 4,017 claims made,
334 relate to a claimant who has died.
‘Balance of probabilities’
Patient’s medical records,
“all scientific evidence”
Rishi Sunak
“We are taking steps to reform vaccine damage payments schemes by modernising the operations and providing more timely outcomes, but of course I'd be happy to talk to the honourable gentleman further about it.”
Mrs. Sheila Ward
Stephen, 57,
Oxford AZ in March 2021
Mr Ward had no pre-existing conditions
Headache after a few days
Taken to hospital, treated for stroke
Bleeds and clots on his brain
Coroner’s certificate, vaccine as one of the causes
“For anyone who has been left with a lifelong disability or young children, it simply wouldn’t be enough to replace somebody's income.”
Ms Spit
“The [60 per cent disabled] criteria is a really big [issue],
because there are so many people just left with nothing after being severely injured,
and have life-changing disabilities,
‘well you’re not interested enough’
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety.html
Note, and limiting the spread of the virus that causes it.
https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html
Groups recommended for vaccination
COVID-19 vaccination is recommended for everyone ages 6 months and older in the United States for the prevention of COVID-19.
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Sweden, lockdowns did not work
Sweden, Lockdown was never on the agenda
https://www.telegraph.co.uk/news/2023/03/23/anders-tegnell-swedens-pandemic-plan-lockdown-never-agenda/
Dr. Anders Tegnell
‘Lockdown was never on the agenda in Sweden’
Sweden’s state epidemiologist (medical)
UK, SPI-B (Scientific Pandemic Influenza Group on Behaviour)
To increase adherence,
“perceived level of personal threat needs to be increased”
Professor Neil Ferguson (Imperial College)
Letting the virus spread freely in the UK
510,000 deaths
Anders Tegnell
“If you put numbers into models and you don’t know those numbers are fairly much correct, you can arrive at very, very strange results.”
“You need to weigh together different sources of science and then you can maybe arrive at something that’s reasonably, hopefully true,”
“And you need to really double-check and see if you get more people doing the same thing before you can feel reasonably safe. But to rely very much on just one study, one model, that’s quite dangerous.”
Swedish people, advised to work from home wherever possible
Ban on gatherings of over 50 people
A few rules for restaurants
Other Covid measures, entirely voluntary
Johan Giesecke, (previous state epidemiologist)
“apolitical – one of those people who did what they were supposed to without reflecting too much on what was expedient or politically viable at the time”
Anders Tegnell
“If you go back to the Spanish flu (1918-19), you can find instances when they tried to lock things down,”
“But in all the pandemic plans we have been discussing during the last decades, closing down a society has never even been on the agenda.”
Shutting down short term?
“I mean, if you know that your healthcare system needs a few weeks to ramp up the ICU and so on, there are instances when such things can be a solution.”
Airborne respiratory virus was going to sweep through the population anyway,
The best you could hope for was to slow it down while protecting the vulnerable
The cost of lockdown would be horrifyingly high
Was the world influenced by China?
‘China is, of course, a state where draconian things like that can be done,”
“And it did work to a certain extent.
So, for a while, there was an idea that we should have very strict measures like a hammer coming down. Bam!
Bring the hammer down hard and then take the hammer away and then sort of let it slowly build up again and then, bam!
But that never worked.”
“We learn quite soon that it’s easy to start having different kinds of restrictions, but it’s very difficult to stop having them.”
No billboards with scary pictures of Covid patients,
no masks, no street furniture of fear
Mobile phone records, Swedes chose to restrict travel and social activities
People told it was safest to be outdoors
Swedish national parks very busy
Denmark and Norway
Closed all schools on March 11th
Sweden
Over-16s and university, moved to remote learning
Younger children, in class as normal
March 13, Johan Giesecke to Anders Tegnell
Don’t you know, my son, with how little wisdom the world is governed?
Anders Tegnell
“The world has gone mad”
In Sweden, it’s even written into the law that the health care should be driven by evidence-based medicine and that was so quickly left behind in other places.”
Stefan Lofven, Sweden’s prime minister
Played no part in the 2pm daily press briefings
Telegraph
there was no baying for blood like there was from the British media as broadcasters with GCSE biology screeched at hapless UK ministers to hurry up and shut the schools.
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Professor Clancy reviews TGA vaccine report
Therapeutic Goods administration
January 2021
https://www.tga.gov.au/sites/default/files/foi-2389-06.pdf
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Things we were not told about the vaccines in 2021
Therapeutic Goods administration
January 2021
https://www.tga.gov.au/sites/default/files/foi-2389-06.pdf
Page 4
“Almost similar microscopic lung inflammation was observed in both challenged control and immunised animals (macaques) after the peak of infection (Days 7/8)”
Challenged with infection, (unvaccinated) control animals
Almost similar microscopic lung inflammation
Challenged with infection, immunized (vaccinated) animals
Almost similar microscopic lung inflammation
Page 4
“There are no distribution and degradation data on the S antigen-encoding mRNA.”
A new therapy that uses an intra-cellular pathway to use intracellular ribosomes
We know from page 45 the lipid nanoparticles are systemically distributed,
But the spike protein that the RNA produces, distribution not tested
No data on how long the spike protein persists
Page 5
“Antibodies and T cells in monkeys declined quickly over 5 weeks after the second dose of BNT162b2 (V9), raising concerns over long term immunity”
Page 6 – A few unknowns were identified by the TGA
“Short term protection studies,
lack of pharmacokinetic data for the S antigen-encoding mRNA (BNT162b2 V9),
suboptimal dosing interval in the repeat dose study,
lack of repeat dose toxicity studies in a second species,
and genotoxicity studies with the novel excipients,
(a substance formulated alongside the active ingrediants)
and lack of studies investigating potential for autoimmune diseases were noted.”
Page 6 – Unknown go on
“Long term immunity,
vaccine induced autoimmune diseases were not studied in the nonclinical program”
Page 8
“BNT162b2 immunisation also induced proinflammatory cytokines such as GM-CSF, TNF-α, IL-6 and IL-18, in addition to IFN-γ, in splenocytes.”
Page 9
“One study found that among people who had recovered from COVID-19, 100% had S protein-specific CD4+ T cells in the circulation and 70% had S protein-specific CD8+ T cells in the circulation
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Australian government data from January 2021
TGA Pfizer document
https://www.tga.gov.au/sites/default/files/foi-2389-06.pdf
Tissue distribution (lipid nanoparticles encapsulation RNA)
(Page 44)
Rats after i.m. vaccine injection
The concentration of radioactive lipid marker reached the peak level in plasma (8.9 μg lipid eqv/mL),
between 1 – 4 h post-dose,
and distribution mainly into liver, adrenal glands, spleen and ovaries over 48 h
Concentrations were higher in plasma than in blood, with mean blood: plasma ratios of 0.5 – 0.6.
DISTRIBUTION (page 40)
The distribution of LNP-BNT162b2 (V9) mRNA or expressed S protein was not studied.
Table 4-2. Mean concentration of radioactivity (sexes combined) in tissue and blood following a single IM dose of 50 μg mRNA/rat
(page 45)
Mean total radioactivity was greatest at the injection site followed by the liver,
with much lower total recovery in spleen, adrenal glands and ovaries
The tissue distribution pattern was similar in 100 μg mRNA/animal dose group as noted above for 50 μg mRNA/animal dose,
with highest distribution into liver, adrenal glands and spleen.
Conclusions
Slow but significant distribution of lipid nanoparticles from the site of injection with major uptake into liver.
Minor distribution in spleen, adrenal glands and ovaries over 48 h.
Mean blood:plasma ratios of 0.5-0.6 indicating nanoparticles mainly present in plasma fraction of blood with peak concentrations in plasma at approx. 2 h post-dose.
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What Australian government knew, January 2021
Australian Government document on Pfizer vaccine dated January 2021 with Senator Rennick. Thank you Senator.
https://www.tga.gov.au/sites/default/files/foi-2389-06.pdf
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Contradictory information on post covid myocarditis
The Incidence of Myocarditis and Pericarditis in Post COVID-19 Unvaccinated Patients-A Large Population-Based Study
https://pubmed.ncbi.nlm.nih.gov/35456309/
The authors declare no conflict of interest.
Myocarditis and pericarditis are potential post-acute cardiac sequelae of COVID-19 infection,
arising from adaptive immune responses.
We aimed to study the incidence of post-acute COVID-19 myocarditis and pericarditis.
Retrospective cohort study
N = 196,992 adults after COVID-19 infection
Clalit Health Services members in Israel
March 2020 and January 2021
The control cohort (no infection)
N = 590,976 adults
Age- and sex-matched
COVID infection cohort
Nine post-COVID-19 patients developed myocarditis (0.0046%)
Eleven patients were diagnosed with pericarditis (0.0056%).
Non- COVID infection cohort
27 patients had myocarditis (0.0046%)
52 had pericarditis (0.0088%)
Age adjusted hazard ratio
0.96
95% confidence interval, 0.93 to 1.00
Male sex, aHR 4.42; were associated with myocarditis
Male sex aHR 1.93; were associated with pericarditis
Post COVID-19 infection was not associated with either myocarditis or pericarditis
aHR 1.08; for myocarditis
aHR 0.53; for myocarditis
We did not observe an increased incidence of neither pericarditis nor myocarditis in adult patients recovering from COVID-19 infection.
Myocarditis and pericarditis (21st March 2022)
https://www.gov.uk/government/publications/covid-19-vaccination-myocarditis-and-pericarditis-information-for-healthcare-professionals/information-for-healthcare-professionals-on-myocarditis-and-pericarditis-following-covid-19-vaccination
In 2017
https://www.ahajournals.org/doi/10.1161/circ.140.suppl_1.11463
About 2,000 hospital admissions for myocarditis
Two-thirds of cases were in men
Median age for men, 33
Mostly viral
https://www.mdpi.com/2077-0383/10/4/603
Presentation of acute myocarditis
Subclinical disease too,
heart failure, chest pain, shortness of breath, palpitations and fatigue.
Dilated cardiomyopathy and chronic heart failure
Sudden death syndrome
https://www.sciencedirect.com/science/article/abs/pii/S0033062009000966?via%3Dihub
Myocarditis implicated in 12% of sudden deaths under the age of 40
Acute pericarditis
Often similar presentation
Some concurrent myocardial involvement (myopericarditis)
Constrictive pericarditis is uncommon
https://heart.bmj.com/content/101/14/1159
Can myocarditis or pericarditis be caused by coronavirus (COVID-19) infection?
It is now recognised that COVID-19 infection can lead to myocarditis or pericarditis
https://pubmed.ncbi.nlm.nih.gov/34516657/
Professional athletes are an atypical group
Published online 2021 May 27
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160916/
1,597 athletes with recent SARS-CoV-2 infection
(March 1, 2020, through December 15, 2020)
0.31% were diagnosed with myocarditis using a symptom-based screening
2.3% were diagnosed with clinical or subclinical myocarditis using cardiac magnetic resonance screening
Is there an association of myocarditis or pericarditis following COVID-19 vaccination?
Many studies have now shown that there is an increased risk of myocarditis following vaccination with an mRNA vaccine,
https://www.nejm.org/doi/full/10.1056/NEJMoa2110737
https://www.cdc.gov/mmwr/volumes/70/wr/mm7027e2.htm
https://www.nejm.org/doi/full/10.1056/NEJMoa2109730
https://www.gov.uk/government/publications/myocarditis-and-pericarditis-after-covid-19-vaccination
especially in young men under the age of 40.
Many of the studies have only limited follow up ……
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More covid vaccines correlated with excess deaths
Is there a Link between the 2021 COVID-19 Vaccination Uptake in Europe and 2022 Excess All-Cause Mortality?
https://www.preprints.org/manuscript/202302.0350/v1
(Western Norway University of Applied Sciences).
Conflict of interest statement
The authors declare no conflict of interest.
We primarily study a possible link between 2021 COVID-19 vaccination uptake in Europe,
and monthly 2022 excess all-cause mortality,
(i.e., mortality higher than before the pandemic)
Analyses of 31 countries, Jan to September, 2022
31 EU member states, plus Norway, Iceland, Liechtenstein, Switzerland
All-cause mortality,
increased more the higher the 2021 vaccination uptake
Countries with more covid vaccines in 2021 had higher excess mortality in first 9 months of 2022
Positive correlation between vaccination in 2021 and excess deaths in 2022
A one percentage point increase in 2021 vaccination uptake,
was associated with a monthly mortality increase in 2022 by 0.105%
(95% CI, 0.075-0.134).
When controlling for alternative explanations
The association remained robust
2021 all-cause mortality
Was lower the higher the vaccination uptake
Inverse correlation between previous covid vaccination and all-cause mortality in 2021
(this association became non-significant when controlling for alternative explanations)
Eurostat
https://ec.europa.eu/eurostat/databrowser/view/demo_mexrt/default/table?lang=en.
EU experienced excess all-cause mortality in the first nine months of 2022
COVID-19 vaccination has prevented SARS- CoV-2-related hospital admission and deaths
Lancet (5th May 2021)
https://pubmed.ncbi.nlm.nih.gov/33964222/
BMJ (13th May 2021)
https://pubmed.ncbi.nlm.nih.gov/33985964/
COVID-19 vaccination has side effects such as myocarditis and pericarditis
JAMA Cardiology (1st June 2022)
https://pubmed.ncbi.nlm.nih.gov/35442390/
JAMA (25th Jan 2022)
https://pubmed.ncbi.nlm.nih.gov/35076665/
A recent study falsified a suspected association between the two diagnoses and COVID-19 virus infection
Journal of Clinical Medicine (15th April 2022)
https://pubmed.ncbi.nlm.nih.gov/35456309/
Post COVID-19 infection was not associated with either myocarditis or pericarditis
Vaccination uptake is the percentage of the total population that has received a “primary course” by week 52, 2021.
The interaction between vaccination up- take and time passed in months since the beginning of 2022 is strongly significant and implies that the mortality increases the higher the vaccination uptake.
Potential reverse causality
Could the excess mortality have caused the increase in vaccinations?
Concerning alternative explanations
We controlled for average all-cause mortality in 2020 and 2021,
divided by the average between 2016 and 2019
Relatively low mortality at one period is followed by relatively high mortality later, and vice versa.
We still observed a significant association between 2021 vaccination uptake and the 2022 monthly increase in all-cause mortality.
Concerning ecological fallacy
We are cautious about making individual-level inferences from our nation-level findings.
Excess mortality, delayed diagnosis or medical treatment
We cannot see that the issues have been more prevalent in high-vaccination vs. low-vaccination countries.
I.e., we do not expect delayed diagnosis or medical treatment during COVID-19 to substantially have induced omitted variable bias.
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Lab leak conspiracy
The proximal origin of SARS-CoV-2
https://www.nature.com/articles/S41591-020-0820-9
https://www.dailymail.co.uk/news/article-11582583/Elon-Musk-slams-Fauci-infamous-science-quote-refuted-criticism-COVID-policy.html
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Excess deaths, could covid vaccines be a factor
Europe excess deaths
https://ec.europa.eu/eurostat/databrowser/view/demo_mexrt/default/bar?lang=en
Our world in data, excess deaths
https://ourworldindata.org/grapher/excess-mortality-p-scores-average-baseline?time=2022-08-14..latest&country=AUS~CAN~NZL~NLD~GBR~USA~IRL
On 5th March 2023, v 5 year average, all ages
https://ourworldindata.org/grapher/excess-mortality-p-scores-average-baseline?tab=table&time=2022-08-14..latest&country=AUS~CAN~NZL~NLD~GBR~USA~IRL
Australia, 16%
Brazil, 10%
Canada, 2%
Ireland, 31%
Netherlands, 6%
NZ, 13%
Scotland, 5%
UK, 3%
US, 2%
Bulgaria, - 20%
Czechia, - 6%
Germany, - 1%
Poland, - 10%
Sweden, -13%
UK, ONS (14th March)
https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19latestinsights/deaths
UK, Week ending 3 March 2023
562 deaths involving COVID-19 registered
Deaths involving COVID-19 accounted for 4.1% of all deaths
13,593 deaths were registered in the UK
7.1% above the five-year average.
Excess deaths, March 2020 to December 2022
Above the five-year average in 18 out of 34 months
Excess deaths, all causes, England and Wales
= 167,356
103,585 were male
63,770 were female
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Vitamin D reduced dementia by 40%
Mosquito net distribution in Uganda, donations to this project, https://www.buymeacoffee.com/awmedicalvideos
More videos from this project, https://www.youtube.com/channel/UCzsLklGgOttU3Se-WGLp7ow
Vitamin D supplementation and incident dementia: Effects of sex, APOE, and baseline cognitive status
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/dad2.12404
Alberta, Canada
Known association, vitamin D deficiency, incident dementia
https://nutritionj.biomedcentral.com/articles/10.1186/s12937-015-0063-7
Role of supplementation is unclear.
Prospectively study
Associations, vitamin D supplementation and incident dementia
N = 12,388 dementia-free people
(from the National Alzheimer's Coordinating Center)
Methods
Baseline exposure to vitamin D was considered D+
No exposure prior to dementia onset was considered D−
MCI and depression were both more frequent in the D− group, compared to D+
People taking vitamin D had less MCI and less depression
Adjusted for age, sex, education, race, cognitive diagnosis, depression, and apolipoprotein E (APOE) ε4.
Potential interactions between exposure and model covariates were explored.
Results
Across all formulations,
vitamin D exposure was associated with significantly longer dementia-free survival,
and lower dementia incidence rate than no exposure
Hazard ratio = 0.60
(95% confidence interval:
0.55–0.65)
Vitamin D exposure was associated with 40% lower dementia incidence versus no exposure.
Over 10 year follow up of
12,388
2,696 participants progressed to dementia
Among them the 2,696
2,017 (74.8%) had no exposure to vitamin D
679 (25.2%) had baseline exposure
Exposure to vitamin D was associated with significantly higher dementia-free survival
5-year survival for D− was 68.4%
5-year survival for D+ was 83.6%
The effect of vitamin D on incidence rate differed significantly,
Vitamin D effects were significantly greater in females versus males
Vitamin D effects were significantly greater in normal cognition versus mild cognitive impairment.
Vitamin D effects were significantly greater in apolipoprotein E ε4 non-carriers versus carriers.
Vitamin D effects were less significantly apolipoprotein E ε4 carriers. (25% one copy, 3% two copies)
Vitamin D has potential for dementia prevention, especially in the high-risk strata.
Vitamin D deficiency, worldwide prevalence of up to 1 billion.
https://www.sciencedirect.com/science/article/pii/S0002916523119277?via%3Dihub
Mechanism of action
https://www.nature.com/articles/s41430-020-0558-y
Vitamin D is known to participate in the clearance of amyloid beta (Aβ) aggregates,
one of the hallmarks of Alzheimer's disease (AD),
and may provide neuroprotection against Aβ-induced tau hyperphosphorylation
(neurofibrillary tangles)
Cholecalciferol may be more effective than ergocalciferol
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Lab leak, Senate and House vote unanimously for intelligence disclosure
Download free, posters and my text books, https://drjohncampbell.co.uk/
Oxford University
https://www.telegraph.co.uk/news/2023/03/10/scientists-dismissed-covid-lab-leak-theory-feared-ban-high-risk/
Anton van der Merwe, professor, molecular immunology
Wuhan researchers were importing bat coronaviruses,
had applied for grants to increase their infectiousness
(gain-of-function research)
False impression given in journals
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext
We stand together to strongly condemn conspiracy theories suggesting that COVID-19 does not have a natural origin.
Bob Seely MP
It’s pathetic
You have this unholy and unethical alliance of scientists working together through highly influential publications effectively to kibosh what may be a scientific truth,
and get it pushed into the realms of conspiracy theory.
We need to be asking tough questions about the origins,
otherwise who knows what virus will be released next,
through incompetence and ambition and how many more millions it will be killing.
This is not some political game. We’ve got to find out where this thing came from.
If you had a virus that suddenly emerged a few hundred yards from Porton Down, this country would never be able to get away with it.
(Or a few miles from Camp Detrick, Maryland)
Anton van der Merwe, professor, molecular immunology
The conflict arises from the fact the researchers perform, and want to continue to perform, precisely the sorts of experiment that make a lab leak much more likely.
These include gain-of-function experiments, where they investigate whether they can enable, by genetic modification, an animal virus to infect human cells.
It is argued that this could help us identify potentially dangerous organisms in the wild and so prevent a pandemic. This seems unlikely.
What is more likely is that these organisms will infect those doing the experiments, who could unwittingly spread the virus to the community, and possibly the whole world
little justification for doing such experiments, except scientific curiosity and the desire for prestige
US position, Wuhan Institute of Virology
Case will be proved soon
Senate unanimously passed bill last week
https://www.telegraph.co.uk/world-news/2023/03/10/joe-biden-forced-declassify-intelligence-covid-19-origins/
https://www.foxnews.com/politics/house-dems-gop-vote-unanimously-declassify-covid-origins-intel-send-bill-biden
House of Representatives
Republicans and Democrats voted, 419 – 0
Require Director of National Intelligence (Avril Haines) to declassify all intelligence
That includes,
activities performed by the Wuhan Institute of Virology with or on behalf of the People’s Liberation Army
coronavirus research or other related activities performed at the Wuhan Institute of Virology prior to the outbreak of Covid-19
WIV workers who got sick
90 days could be allowed after passing a bill
Department of Energy and the FBI
House Permanent Select Intelligence Committee Chairman Mike Turner
The American public deserves answers to every aspect of the COVID-19 pandemic,
including how this virus was created and specifically,
whether it was a natural occurrence of was the result of a lab-related event
Dr Robert Redfield
former director of the Centers for Disease Control and Prevention
I still believe today that the data indicates that the outbreak of Covid 19 was more likely the result of a lab leak than as a result of a natural spillover event
Representative Greg Murphy
Believes Dr. Anthony Fauci, knew it came from the Wuhan lab and tried to cover it up.
In January of 2020, Dr. Fauci received emails that promulgated that COVID-19 looked engineered and not from the wild,
Yet three weeks later, to save his own skin, he commissioned a scientific paper which ‘debunked’ the lab theory.
He was academically and intellectually dishonest.
The truth is that Dr. Fauci and his institution funneled hundreds of thousands of dollars of taxpayer money to promote dangerous gain-of-function research at the Wuhan Institute of Virology without proper guardrails
Rep. Jim Himes
There’s not one iota of evidence for any of that
(Still wants evidence released)
At every juncture, the People's Republic of China government has obfuscated and obstructed legitimate inquiries and investigations into the origins of the disease
China’s approach has been deeply irresponsible and dangerous to global public health
Mr Hancock
Asked to remove passages from Pandemic Diaries
Questioned the official Chinese version
https://www.telegraph.co.uk/news/2023/03/09/wuhan-lab-leak-theory-back-frame-no-10-vows-not-discount/
Simon Case, Cabinet Secretary
Concerns, they would cause problems
could damage national security
Cabinet Office
Entirely coincidental that Covid-19 was discovered close to a Chinese government laboratory.
Spokesman for Rishi Sunak
The UK wants to see a robust, transparent and science-led review and believes all possibilities remain on the table until that is concluded.
(if evidence is presented by the World Health Organisation)
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Professor Clancy, learning from the pandemic
Covid-19: insights gained, lessons unheeded. Direct link to professor Clancy’s Quadrant articles.
https://quadrant.org.au/writer/robert-clancy/
Professor Robert Clancy is a consultant physician, immunologist, emeritus professor of pathology, doctor of science, doctor of philosophy, author, communicator, and teacher of medicine. Robert holds the Order of Australia decoration.
Direct link to professor Clancy’s Quadrant articles.
https://quadrant.org.au/writer/robert-clancy/
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Marc Girardot, Unified Bolus Theory
Superb review from Marc Girardot on inadvertent intravenous administration of vaccines. This evidence and analysis demands a response from regulators around the world. If this is not forthcoming, I consider the regulators negligent.
Follow Marc on Substack, https://substack.com/profile/7635404-marc-girardot
When and How Can Vaccine Particles Hurt You? - A Visualisation Exercise
https://covidmythbuster.substack.com/p/when-and-how-can-vaccine-particles
Or Twitter, https://twitter.com/GirardotMarc
Complications of injectable testosterone undecanoate in routine clinical practice
https://pubmed.ncbi.nlm.nih.gov/25637074/
https://academic.oup.com/ejendo/article-abstract/172/5/511/6660844?login=false
Covid myth buster series
https://covidmythbuster.substack.com
Intravenous Injection of Coronavirus Disease 2019 (COVID-19) mRNA Vaccine Can Induce Acute Myopericarditis in Mouse Model
https://pubmed.ncbi.nlm.nih.gov/34406358/
Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration
https://pubmed.ncbi.nlm.nih.gov/35486845/
Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factor
https://pubmed.ncbi.nlm.nih.gov/19953082/
Intravenous administration of recombinant adenoviruses causes thrombocytopenia, anemia and erythroblastosis in rabbits
https://pubmed.ncbi.nlm.nih.gov/10738553/
A Prospective Study of the Incidence of Myocarditis/Pericarditis and New Onset Cardiac Symptoms following Smallpox and Influenza Vaccination
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368609/
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Dr Suneel Dhand, from line doctor
Great discussion with Suneel on the acute phases of the pandemic
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Vaccine research rushed?
ovid not deadly enough to fast-track vaccines, Chris Whitty advised ministers
Chief Medical Officer gave opinion in February 2020 after Dominic Cummings mentioned Israel was planning to inoculate population
https://www.telegraph.co.uk/news/2023/03/07/covid-not-deadly-enough-fast-track-vaccines-chris-whitty-advised/
Prof Sir Chris Whitty told Matt Hancock
Diseases with a mortality rate in the range of 1%
would need a “very safe” vaccine
the necessary clinical trials would be a “rate limiting step”.
May 2021 Mr Cummings
Told a Covid group of MPs
“unarguable” that the vaccine trials process should have happened more quickly.
Taken “literally hours” for a vaccine to be invented in January 2020
Government should have recruited 5,000-10,000 for human challenge trials
(Human challenge trials started in January 2021)
Preparing for a successful spring 2023 COVID-19 booster campaign
https://www.england.nhs.uk/long-read/preparing-for-a-successful-spring-2023-covid-19-booster-campaign/
Booster campaign in England, April 17 to June 30.
Adults aged 75 years and over
Residents in a care home for older adults
Individuals aged 5 years and over who are immunosuppressed
Vaccination, six months after previous dose
Millions now able to book their autumn booster
(7 September 2022)
https://www.england.nhs.uk/2022/09/millions-now-able-to-book-their-autumn-booster/
Resident Jean Rosebuck said: “I wanted the vaccine so it doesn’t go around the carers and other residents”.
Fellow resident Tom Spinks, 80, said: “I wanted to get the booster because it keeps everyone safe and gives me peace of mind”.
What about the CDC?
https://www.cdc.gov/coronavirus/2019-ncov/index.html
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html
https://covid.cdc.gov/covid-data-tracker/#datatracker-home
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Matt Hancock leaks
Matt Hancock's plan to ‘frighten the pants off everyone’ about Covid
https://www.telegraph.co.uk/news/2023/03/04/project-fear-covid-lockdown-files-matt-hancock-whatsapp/
How health secretary hoped to shock public into complying with ever-changing lockdown rules
How Matt Hancock sought to hog the Covid vaccine limelight
https://www.telegraph.co.uk/news/2023/03/05/matt-hancock-triumph-covid-vaccine-lockdown-files-whatsapp/
Matt Hancock chose saving face over ending unnecessary ‘pingdemic’
https://www.telegraph.co.uk/news/2023/03/05/chris-whitty-matt-hancock-covid-isolation-pingdemic-whatsapp/
At points, 600,000 pinged per week (who had been in close proximity to a Covid case)
Policy resulted in more than 20 million people being told to self-isolate,
regardless of whether they had symptoms.
At that stage, the self-isolation period was 14 days.
Fortnight-long quarantine applied to both contacts of Covid cases and returning travellers.
A month later isolation period was reduced to 10 days
Scheme not scrapped until Feb 2022
Matt Hancock jokes about Bill Gates
https://www.telegraph.co.uk/news/2023/03/05/matt-hancock-joke-bill-gates-covid-vaccine-conspiracy-theory/
New Variant Assessment Platform (NVAP)
Offered UK expertise to assess new variants around the world
Many conspiracy theories, were said to have been spread on by pro-Kremlin outlets.
Mr Gates did not, in the event, endorse the New Variant Assessment Platform.
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